Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 3/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | TSPO | P30536 | 2/20 | 0.34 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24683217 | 1.00 | MAPK8 (0.38) | MAPK8MAPK9MAPK10KMT2AMCL1 | |
| SCHEMBL24683205 | 0.89 | LMNA (0.38) | KMT2AMCL1MEN1HSP90AA1KDM4E | |
| SCHEMBL29799927 | 0.89 | LMNA (0.38) | KMT2AMCL1MEN1HSP90AA1KDM4E | |
| SCHEMBL30664726 | 0.89 | HSP90AA1 (0.37) | KMT2AMEN1HSP90AA1MAPTTSPO | |
| SCHEMBL24683855 | 0.89 | HSP90AA1 (0.37) | KMT2AMEN1HSP90AA1MAPTTSPO | |
| SCHEMBL24683191 | 0.88 | HSP90AA1 (0.38) | KMT2AATMMEN1HSP90AA1KDM4E | |
| SCHEMBL30664665 | 0.88 | HSP90AA1 (0.38) | KMT2AATMMEN1HSP90AA1KDM4E | |
| SCHEMBL29799950 | 0.85 | MAPT (0.38) | MAPK8KMT2AMCL1MEN1KDM4E | |
| SCHEMBL24683203 | 0.85 | HSP90AA1 (0.39) | KMT2AMEN1HSP90AA1MAPTTSPO | |
| SCHEMBL29799821 | 0.85 | HSP90AA1 (0.39) | KMT2AMEN1HSP90AA1MAPTTSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240174629-A1 | 2-ACETAMIDO-6-HYDROXY-BENZOTHIOPHENE DERIVATIVES WITH ANTIVIRAL ACTIVITY | OTCPHARM JSC (RU) | 2024-05-30 | — | — | US | disclosed |
| EP-4293017-A1 | 2-ACETAMIDO-6-HYDROXY-BENZOTHIOPHENE DERIVATIVES WITH ANTIVIRAL ACTIVITY | Otcpharm JSC (RU) | 2023-12-20 | — | — | EP | disclosed |
| CN-117222630-A | 2-acetamido-6-hydroxy-benzothiophene derivatives having antiviral activity | OTC制药公司(JSC) | 2023-12-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240174629-A1 | 2-ACETAMIDO-6-HYDROXY-BENZOTHIOPHENE DERIVATIVES WITH ANTIVIRAL ACTIVITY | ACE2, ACE, EIF2AK2 | MAPK8 3884/4885MAPK9 1869/4885MAPK10 2312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.