Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP4 | P12644 | 7/20 | 1.00 |
| ▸ | ACVR1 | Q04771 | 12/20 | 0.55 |
| ▸ | ACVR1B | P36896 | 11/20 | 0.55 |
| ▸ | ACVRL1 | P37023 | 10/20 | 0.55 |
| ▸ | BMPR1B | O00238 | 9/20 | 0.55 |
| ▸ | BMPR1A | P36894 | 9/20 | 0.55 |
| ▸ | KDR | P35968 | 6/20 | 0.55 |
| ▸ | TGFBR1 | P36897 | 5/20 | 0.55 |
| ▸ | PRKAB1 | Q9Y478 | 5/20 | 0.55 |
| ▸ | TGFBR2 | P37173 | 4/20 | 0.55 |
| ▸ | JAK1 | P23458 | 1/20 | 0.54 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.54 |
| ▸ | BMPR2 | Q13873 | 3/20 | 0.51 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.50 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.50 |
| ▸ | ACVR2A | P27037 | 1/20 | 0.50 |
| ▸ | ACVR2B | Q13705 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11953871 | 1.00 | BMP4 (1.00) | BMP4ACVR1ACVR1BACVRL1BMPR1B | |
| SCHEMBL30547944 | 0.91 | BMP4 (0.84) | BMP4ACVR1ACVR1BACVRL1BMPR1B | |
| SCHEMBL30074621 | 0.79 | BMP4 (0.70) | BMP4ACVR1ACVR1BACVRL1BMPR1B | |
| SCHEMBL2059666 | 0.79 | BMP4 (0.70) | BMP4ACVR1ACVR1BACVRL1BMPR1B | |
| SCHEMBL11953449 | 0.78 | BMP4 (1.00) | BMP4ACVR1ACVR1BACVRL1BMPR1B | |
| SCHEMBL16112179 | 0.75 | BMP4 (0.80) | BMP4ACVR1ACVR1BACVRL1BMPR1B | |
| SCHEMBL16112689 | 0.75 | BMP4 (0.68) | BMP4ACVR1ACVR1BACVRL1BMPR1B | |
| SCHEMBL1227713 | 0.75 | CYP1A2 (0.60) | BMP4TGFBR1TGFBR2GRM4 | |
| SCHEMBL29699887 | 0.75 | CYP1A2 (0.60) | BMP4TGFBR1TGFBR2GRM4 | |
| SCHEMBL27917128 | 0.75 | CYP1A2 (0.60) | BMP4TGFBR1TGFBR2GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |
| US-20230392115-A1 | METHODS FOR MAKING AND USING DIFFERENTIATED NEURAL CELLS | RESEARCH DEVELOPMENT FOUNDATION (US) | 2023-12-07 | — | — | US | disclosed |