SCHEMBL30547944

SCHEMBL30547944

c1cc(-c2cnn3cccnc23)c2cccnc2c1

nearest known ligand 0.84

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ BMP4 P12644 5/20 0.84
▸ ACVR1 Q04771 16/20 0.57
▸ ACVRL1 P37023 15/20 0.57
▸ BMPR1B O00238 14/20 0.57
▸ BMPR1A P36894 13/20 0.57
▸ KDR P35968 3/20 0.57
▸ ACVR1B P36896 9/20 0.52
▸ TGFBR1 P36897 2/20 0.52
▸ TGFBR2 P37173 2/20 0.52
▸ PRKAB1 Q9Y478 2/20 0.52
▸ BMPR2 Q13873 1/20 0.52
▸ JAK1 P23458 1/20 0.51
▸ PIK3C3 Q8NEB9 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30665011 0.91 BMP4 (1.00) BMP4ACVR1ACVRL1BMPR1BBMPR1A
SCHEMBL11953871 0.91 BMP4 (1.00) BMP4ACVR1ACVRL1BMPR1BBMPR1A
SCHEMBL198641 0.77 MAPT (0.64) BMP4ACVR1
SCHEMBL16111462 0.76 BMP4 (0.85) BMP4ACVR1ACVRL1BMPR1BBMPR1A
SCHEMBL12779951 0.76 ACVRL1 (0.78) BMP4ACVR1ACVRL1BMPR1BBMPR1A
SCHEMBL30074632 0.75 BMP4 (0.57) BMP4TGFBR1JAK1PIK3C3
SCHEMBL16111478 0.75 ACVRL1 (0.70) BMP4ACVR1ACVRL1BMPR1BBMPR1A
SCHEMBL24181952 0.73 BMP4 (0.51) BMP4JAK1PIK3C3
SCHEMBL11953869 0.73 ACVR1 (1.00) BMP4ACVR1ACVRL1BMPR1BBMPR1A
Hydrochloric Acid SCHEMBL30172429 0.72 BMP4 (0.50) BMP4ACVR1ACVRL1BMPR1BBMPR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12383624-B2 Cargo delivery system and composition comprising the same SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2025-08-12 — — US claimed
US-12383624-B2 Cargo delivery system and composition comprising the same SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2025-08-12 — — US disclosed
US-20230190938-A1 NOVEL CARGO DELIVERY SYSTEM AND COMPOSITION COMPRISING THE SAME SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2023-06-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230190938-A1 NOVEL CARGO DELIVERY SYSTEM AND COMPOSITION COMPRISING THE SAME ATG7, SQSTM1, BECN1 BMP4 3238/4885ACVR1 3474/4885ACVRL1 3047/4885
US-12383624-B2 Cargo delivery system and composition comprising the same ATG7, SQSTM1, BECN1 BMP4 3572/4885ACVR1 3717/4885ACVRL1 3409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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