Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 3/20 | 0.75 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.75 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 4/20 | 0.68 |
| ▸ | RAB9A | P51151 | 4/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | CRHBP | P24387 | 1/20 | 0.68 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2698258 | 1.00 | P2RX1 (0.75) | P2RX1P2RX4P2RX7SMN1; SMN2PTGS1 | |
| SCHEMBL18327174 | 0.86 | LMNA (0.89) | SMN1; SMN2NPC1RAB9ALMNAMEN1 | |
| SCHEMBL127962 | 0.86 | P2RX1 (1.00) | P2RX1P2RX4P2RX7MEN1KMT2A | |
| SCHEMBL12700361 | 0.84 | NPC1 (0.71) | SMN1; SMN2PTGS1NPC1RAB9AKDM4E | |
| SCHEMBL2638776 | 0.84 | PTGS1 (0.70) | SMN1; SMN2PTGS1NPC1RAB9ALMNA | |
| Salfluverine SCHEMBL2700016 | 0.83 | P2RX1 (1.00) | P2RX1P2RX4P2RX7PTGS1TMPRSS4 | |
| SCHEMBL1828128 | 0.83 | P2RX1 (0.62) | P2RX1P2RX4P2RX7SMN1; SMN2PTGS1 | |
| SCHEMBL31092080 | 0.83 | SMN1; SMN2 (1.00) | SMN1; SMN2PTGS1NPC1RAB9ALMNA | |
| SCHEMBL29168823 | 0.83 | PTGS1 (0.68) | P2RX1P2RX4P2RX7SMN1; SMN2PTGS1 | |
| SCHEMBL1963068 | 0.83 | PTGS1 (1.00) | P2RX1SMN1; SMN2PTGS1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117180260-A | Deoxyflavonoid-based T lymphocyte activity inhibition composition | 杭州卢特康生物科技有限公司 | 2023-12-08 | — | — | CN | disclosed |