Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.65 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.65 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.63 |
| ▸ | PTPRC | P08575 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.56 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.56 |
| ▸ | PTGES | O14684 | 2/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.54 |
| ▸ | F2R | P25116 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21652266 | 0.89 | PTGES (0.62) | PTGS1SMN1; SMN2NPC1RAB9AKCNK3 | |
| SCHEMBL5332281 | 0.88 | KCNK3 (0.75) | PTGS1SMN1; SMN2NPC1RAB9AKCNK3 | |
| SCHEMBL12334663 | 0.88 | RORC (0.71) | PTGS1SMN1; SMN2NPC1RAB9AKCNK3 | |
| SCHEMBL21022150 | 0.87 | LMNA (0.66) | PTGS1SMN1; SMN2NPC1RAB9AKCNK3 | |
| SCHEMBL30791183 | 0.86 | LMNA (0.69) | PTGS1SMN1; SMN2NPC1RAB9AKCNK3 | |
| SCHEMBL8363754 | 0.86 | KCNK3 (0.64) | PTGS1SMN1; SMN2NPC1RAB9AKCNK3 | |
| SCHEMBL678924 | 0.86 | PTGS1 (0.72) | PTGS1SMN1; SMN2KCNK3KCNK9RXFP1 | |
| SCHEMBL96040 | 0.86 | KCNK3 (0.59) | PTGS1SMN1; SMN2KCNK3KCNK9RXFP1 | |
| SCHEMBL3335567 | 0.86 | KCNK3 (0.59) | PTGS1SMN1; SMN2KCNK3KCNK9RXFP1 | |
| SCHEMBL20601679 | 0.84 | KCNK3 (0.66) | PTGS1SMN1; SMN2NPC1RAB9AKCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011524365-A | — | — | 2011-09-01 | — | — | JP | claimed |
| WO-2009152356-A2 | COMPOUNDS AND COMPOSITIONS USEFUL FOR THE TREATMENT OF MALARIA | IRM LLC (BM) | 2009-12-17 | — | — | WO | claimed |