Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.37 |
| ▸ | GRM5 | P41594 | 7/20 | 0.36 |
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26615220 | 1.00 | LMNA (0.38) | LMNAMAPTLTB4RLTB4R2GRM5 | |
| SCHEMBL2319086 | 0.81 | ALDH1A1 (0.36) | LMNAMAPTLTB4RLTB4R2GRM5 | |
| SCHEMBL20554397 | 0.79 | MAOB (0.38) | LMNAMAPTLTB4RLTB4R2GRM5 | |
| SCHEMBL13506258 | 0.77 | MAOB (0.38) | LMNAMAPTLTB4RLTB4R2GRM5 | |
| SCHEMBL13506594 | 0.76 | MAOB (0.42) | LMNAMAPTLTB4RLTB4R2GRM5 | |
| SCHEMBL20554850 | 0.75 | MAOB (0.45) | LMNAMAPTLTB4RLTB4R2GRM5 | |
| SCHEMBL30132570 | 0.75 | MAOB (0.45) | LMNAMAPTLTB4RLTB4R2GRM5 | |
| SCHEMBL30132594 | 0.74 | MAOB (0.55) | GRM5MAOBMAOAALDH1A1HPGD | |
| SCHEMBL20554658 | 0.74 | MAOB (0.55) | GRM5MAOBMAOAALDH1A1HPGD | |
| SCHEMBL23977243 | 0.73 | MAOB (0.40) | LMNAMAPTLTB4RLTB4R2GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947713-A | Ring-merging compound and application thereof | 中国科学院上海药物研究所 | 2023-10-27 | — | — | CN | disclosed |