SCHEMBL30665455

SCHEMBL30665455

CC(=O)C(O)[C@H](N)C(=O)OCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.56
LTA4H P09960 2/20 0.51
LAP3 P28838 1/20 0.51
SLC1A3 P43003 2/20 0.47
SLC1A2 P43004 2/20 0.47
SLC1A1 P43005 2/20 0.47
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
SLC15A1 P46059 2/20 0.47
ELANE P08246 1/20 0.47
MAPK1 P28482 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A3 Q01959 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ALPI P09923 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11310409 0.87 SLC1A1 (0.54) ALDH1A1LTA4HLAP3SLC1A3SLC1A2
SCHEMBL15449774 0.85 ALDH1A1 (0.61) ALDH1A1LTA4HLAP3KMT2AELANE
SCHEMBL14908325 0.83 ALDH1A1 (0.55) ALDH1A1LTA4HLAP3SLC1A3SLC1A2
SCHEMBL17878731 0.83 ALDH1A1 (0.55) ALDH1A1LTA4HLAP3SLC1A3SLC1A2
SCHEMBL216743 0.83 ALDH1A1 (0.55) ALDH1A1LTA4HLAP3SLC1A3SLC1A2
SCHEMBL216744 0.83 ALDH1A1 (0.55) ALDH1A1LTA4HLAP3SLC1A3SLC1A2
SCHEMBL12053128 0.83 ALDH1A1 (0.55) ALDH1A1LTA4HLAP3SLC1A3SLC1A2
SCHEMBL8232952 0.83 ALDH1A1 (0.55) ALDH1A1LTA4HLAP3SLC1A3SLC1A2
SCHEMBL30621984 0.83 ALDH1A1 (0.54) ALDH1A1LTA4HLAP3SLC1A3SLC1A2
SCHEMBL30613144 0.83 ALDH1A1 (0.54) ALDH1A1LTA4HLAP3SLC1A3SLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116947858-A Compounds selectively inhibiting four amino acid modifications of ADP, preparation and application thereof 首都医科大学 2023-10-27 CN disclosed