Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 10/20 | 0.49 |
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.46 |
| ▸ | MAPK3 | P27361 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29270325 | 1.00 | IL1B (0.49) | IL1BNLRP3MAPK3MAPTPROKR1 | |
| SCHEMBL29270332 | 0.86 | IL1B (0.47) | IL1BNLRP3 | |
| SCHEMBL30833948 | 0.86 | IL1B (0.47) | IL1BNLRP3 | |
| SCHEMBL31367801 | 0.86 | IL1B (0.47) | IL1BNLRP3 | |
| SCHEMBL23933514 | 0.82 | GRIN2B (0.39) | IL1BNLRP3 | |
| SCHEMBL23933508 | 0.82 | GRIN2B (0.39) | IL1BNLRP3 | |
| SCHEMBL23933511 | 0.82 | GRIN2B (0.39) | IL1BNLRP3 | |
| SCHEMBL22654862 | 0.81 | IL1B (0.66) | IL1BNLRP3 | |
| SCHEMBL22654864 | 0.81 | IL1B (0.66) | IL1BNLRP3 | |
| SCHEMBL29270329 | 0.81 | NLRP3 (0.43) | IL1BNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4531858-A1 | NOVEL COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2025-04-09 | — | — | EP | disclosed |
| WO-2023232917-A1 | NOVEL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-07 | — | — | WO | disclosed |