Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 13/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 13/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | F11 | P03951 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30665811 | 1.00 | LPL (0.39) | LPLLIPGEGFRCSF1RPRMT5 | |
| SCHEMBL11000 | 0.83 | ATM (0.41) | LPLLIPGCSF1RPRMT5WDR77 | |
| SCHEMBL31468044 | 0.82 | LPL (0.45) | LPLLIPGEGFRCSF1RPRMT5 | |
| SCHEMBL2175008 | 0.81 | PRMT5 (0.45) | LPLLIPGEGFRCSF1RPRMT5 | |
| SCHEMBL15912503 | 0.79 | LPL (0.42) | LPLLIPGCSF1RPRMT5WDR77 | |
| SCHEMBL31730871 | 0.78 | IMPDH2 (0.44) | LPLLIPGCSF1RPRMT5WDR77 | |
| SCHEMBL30742479 | 0.78 | CYP1A2 (0.40) | LPLLIPGPRMT5WDR77F11 | |
| SCHEMBL26879745 | 0.78 | CYP1A2 (0.40) | LPLLIPGPRMT5WDR77F11 | |
| SCHEMBL19896283 | 0.77 | LPL (0.46) | LPLLIPGCSF1RPRMT5WDR77 | |
| SCHEMBL2422531 | 0.76 | NPC1 (0.48) | LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4531858-A1 | NOVEL COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2025-04-09 | — | — | EP | disclosed |
| WO-2023232917-A1 | NOVEL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-07 | — | — | WO | disclosed |