Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL109063 | 1.00 | NPSR1 (0.48) | NPSR1KDM4EALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL31026209 | 0.84 | NPSR1 (0.47) | NPSR1KDM4EALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL29502585 | 0.82 | NPSR1 (0.54) | NPSR1KDM4EALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL117827 | 0.82 | NPSR1 (0.54) | NPSR1KDM4EALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL29556424 | 0.81 | NPSR1 (0.48) | NPSR1KDM4EALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL118992 | 0.81 | NPSR1 (0.48) | NPSR1KDM4EALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL17611040 | 0.81 | NPSR1 (0.44) | NPSR1KDM4EALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL30641345 | 0.81 | ALDH1A1 (0.47) | NPSR1KDM4EALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL16505254 | 0.81 | ALDH1A1 (0.47) | NPSR1KDM4EALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL12338897 | 0.79 | NPSR1 (0.50) | NPSR1KDM4EALDH1A1PKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720061-A1 | TREM2 AGONISTS | F. Hoffmann-La Roche AG (CH) | 2026-04-08 | — | — | EP | disclosed |
| EP-4522608-A1 | PYRROLIDINONE DERIVATIVES AS INHIBITORS OF NF KAPPA B INDUCING KINASE | JANSSEN Pharmaceutica NV (BE) | 2025-03-19 | — | — | EP | disclosed |
| CN-119638669-A | Chemokine receptor antagonist, pharmaceutical composition and application | 上海医药集团股份有限公司 | 2025-03-18 | — | — | CN | disclosed |
| WO-2024246018-A1 | TREM2 AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-12-05 | — | — | WO | disclosed |
| WO-2023217906-A1 | PYRROLIDINONE DERIVATIVES AS INHIBITORS OF NF KAPPA B INDUCING KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-16 | — | — | WO | disclosed |