Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13640315 | 1.00 | MAPT (0.36) | MAPTHTTEGFRTSHRBTK | |
| SCHEMBL5021691 | 0.87 | PPARD (0.34) | MAPTKDM4E | |
| SCHEMBL6664133 | 0.84 | HTT (0.41) | MAPTHTTEGFRTSHRCCNT1 | |
| SCHEMBL23363895 | 0.81 | CCNT1 (0.35) | MAPTHTTEGFRTSHRCCNT1 | |
| SCHEMBL19759439 | 0.77 | SMN1; SMN2 (0.35) | MAPTHTTBTKCDK9KDM4E | |
| SCHEMBL4537605 | 0.76 | GRIN2D (0.42) | — | |
| SCHEMBL15260198 | 0.74 | TSHR (0.39) | MAPTHTTEGFRTSHRKDM4E | |
| SCHEMBL10022793 | 0.72 | MAPT (0.44) | MAPTHTTEGFRTSHRCCNT1 | |
| SCHEMBL9172810 | 0.72 | TSHR (0.43) | MAPTHTTEGFRTSHRCCNT1 | |
| SCHEMBL3373620 | 0.72 | MAPT (0.44) | MAPTHTTEGFRTSHRCCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49735-E1 | Oxazolidinones as modulators of MGLUR5 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-11-28 | — | — | US | disclosed |