Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.34 |
| ▸ | CDK9 | P50750 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30669244 | 0.84 | MAPT (0.36) | HTTKDM4EEGFRMAPTCCNT1 | |
| SCHEMBL13640315 | 0.84 | MAPT (0.36) | HTTKDM4EEGFRMAPTCCNT1 | |
| SCHEMBL23363895 | 0.82 | CCNT1 (0.35) | HTTKDM4EEGFRMAPTCCNT1 | |
| SCHEMBL68962 | 0.78 | KMT2A (0.54) | HTTKMT2AHSD17B10KDM4EMAPT | |
| SCHEMBL15260198 | 0.76 | TSHR (0.39) | HTTKMT2AKDM4EEGFRMAPT | |
| SCHEMBL2067939 | 0.74 | KMT2A (0.46) | HTTKMT2AHSD17B10KDM4EMAPT | |
| SCHEMBL6665940 | 0.74 | NOS3 (0.38) | EGFRCCNT1CDK9NPC1TSHR | |
| SCHEMBL10022793 | 0.73 | MAPT (0.44) | HTTKMT2AEGFRMAPTCCNT1 | |
| SCHEMBL3373620 | 0.73 | MAPT (0.44) | HTTKMT2AEGFRMAPTCCNT1 | |
| SCHEMBL12798326 | 0.73 | EGFR (0.40) | HTTKMT2AEGFRMAPTCCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004013139-A2 | PROCESS FOR PREPARING 7-AZAINDOLES | EISAI CO., LTD (JP) | 2004-02-12 | — | — | WO | disclosed |