Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2835217 | 0.83 | TNK2 (0.36) | HMGCR | |
| SCHEMBL2830195 | 0.70 | KCNH2 (0.44) | KCNH2TSHR | |
| SCHEMBL8591678 | 0.70 | GPR84 (0.35) | KCNH2TSHRADORA3TLR8HMGCR | |
| SCHEMBL28739769 | 0.68 | FFAR1 (0.46) | KCNH2 | |
| SCHEMBL55033 | 0.68 | TSHR (0.53) | TSHRHMGCR | |
| SCHEMBL15287825 | 0.67 | KCNH2 (0.39) | KCNH2ADORA3TLR7PGK1GPR84 | |
| SCHEMBL5886588 | 0.67 | FFAR1 (0.53) | KCNH2 | |
| SCHEMBL16424871 | 0.67 | KCNH2 (0.46) | KCNH2TSHRHMGCRGPR84 | |
| SCHEMBL2233697 | 0.67 | KCNH2 (0.46) | KCNH2TSHRHMGCRGPR84 | |
| SCHEMBL8846653 | 0.65 | FFAR1 (0.51) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117105761-A | Preparation method of 3, 3-disubstituted-1-indenone compound | 湖南师范大学 | 2023-11-24 | — | — | CN | disclosed |