SCHEMBL2835217

SCHEMBL2835217

CCCCC#Cc1c(F)c(F)c(F)c(C(=O)O)c1F

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNK2 Q07912 1/20 0.36
HMGCR P04035 3/20 0.36
HCAR2 Q8TDS4 1/20 0.35
PTPN7 P35236 5/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
TDP1 Q9NUW8 3/20 0.34
KDM4E B2RXH2 2/20 0.34
MAPT P10636 2/20 0.34
FFAR1 O14842 1/20 0.34
FFAR4 Q5NUL3 1/20 0.34
LMNA P02545 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
APEX1 P27695 1/20 0.34
CYP2C19 P33261 1/20 0.34
HSD17B10 Q99714 1/20 0.34
MMP2 P08253 1/20 0.33
MMP12 P39900 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30669308 0.83 KCNH2 (0.35) HMGCR
SCHEMBL2833710 0.81 FFAR1 (0.35) TNK2HMGCRHCAR2PTPN7SMN1; SMN2
SCHEMBL19151796 0.73 MEN1 (0.32) SMN1; SMN2KDM4ECYP1A2MEN1KMT2A
SCHEMBL2835353 0.72 CYP3A4 (0.42) TNK2HMGCRSMN1; SMN2TDP1KDM4E
Tetrabuthylammonium SCHEMBL10748554 0.69 SLC22A1 (0.46) HCAR2SMN1; SMN2CYP3A4HSD17B10ESR1
SCHEMBL19130692 0.69 MEN1 (0.35) HCAR2SMN1; SMN2CYP1A2CYP2C9MEN1
SCHEMBL28549816 0.68 HCAR2 (0.39) HCAR2TDP1FFAR1FFAR4HSD17B10
SCHEMBL5669455 0.68 KDM4E (0.44) TNK2SMN1; SMN2TDP1KDM4EMAPT
SCHEMBL5097670 0.68 FFAR1 (0.48) TNK2HMGCRPTPN7SMN1; SMN2TDP1
Alcohol SCHEMBL27681766 0.67 SMN1; SMN2 (0.45) HCAR2SMN1; SMN2ESR1RECQLMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8263268-B2 Ester compound, and non-aqueous electrolyte solution and lithium secondary battery each using the ester compound UBE INDUSTRIES, LTD. (JP) 2012-09-11 US disclosed
EP-2108640-B1 ESTER COMPOUND, AND NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY EACH USING THE ESTER COMPOUND UBE INDUSTRIES (JP) 2012-07-25 EP disclosed
US-20100119955-A1 ESTER COMPOUND, AND NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY EACH USING THE ESTER COMPOUND UBE INDUSTRIES, LTD. (JP) 2010-05-13 US disclosed
EP-2108640-A1 ESTER COMPOUND, AND NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY EACH USING THE ESTER COMPOUND Ube Industries, Ltd. (JP) 2009-10-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100119955-A1 ESTER COMPOUND, AND NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY EACH USING THE ESTER COMPOUND CEL, LAGE3, PEF1 TNK2 1389/4885HMGCR 2062/4885HCAR2 4144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.