Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | BCL6 | P41182 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 2/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.42 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.42 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30669792 | 0.81 | MAPT (0.58) | PDE10AMAPTDYRK1ACLK2AURKA | |
| SCHEMBL20927824 | 0.78 | PDE10A (0.53) | PDE10AMAPTBCL6DYRK1AAURKA | |
| SCHEMBL7710403 | 0.73 | MAPT (0.50) | PDE10AMAPTDYRK1ACLK2AURKA | |
| SCHEMBL31160460 | 0.71 | MAPT (0.41) | PDE10AMAPTCHEK1DYRK1ACLK2 | |
| SCHEMBL17967624 | 0.71 | MAPT (1.00) | MAPTCHEK1DYRK1ACLK2MET | |
| SCHEMBL1561284 | 0.71 | MAPT (0.81) | MAPTCHEK1 | |
| SCHEMBL20927842 | 0.69 | PDE10A (0.46) | PDE10ABCL6 | |
| SCHEMBL29869934 | 0.69 | AURKA (0.64) | MAPTAURKAAURKBINCENPTPX2 | |
| SCHEMBL23885630 | 0.68 | CHEK1 (0.49) | PDE10AMAPTCHEK1DYRK1ACLK2 | |
| SCHEMBL20928268 | 0.68 | PDE10A (0.42) | PDE10AMAPTCHEK1AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117098763-A | TYK2 inhibitors | 渤健马萨诸塞州股份有限公司 | 2023-11-21 | — | — | CN | disclosed |