Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | SLC43A1 | O75387 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30670557 | 0.86 | ABCB1 (0.39) | MEN1KMT2AGAACHRNA7HTR3E | |
| SCHEMBL21082486 | 0.74 | GAA (0.44) | MEN1KMT2AGAACHRNA7HTR3E | |
| SCHEMBL30158161 | 0.66 | KMT2A (0.43) | MEN1KMT2AGAACHRNA7HTR3E | |
| Methyl Benzoate SCHEMBL27799326 | 0.65 | TSHR (0.56) | KMT2ATSHR | |
| SCHEMBL19320699 | 0.65 | BCHE (0.46) | MEN1KMT2AGAACHRNA7HTR3E | |
| SCHEMBL28699769 | 0.64 | GAA (0.50) | MEN1KMT2AGAACHRNA7HTR3E | |
| SCHEMBL19261912 | 0.64 | LMNA (0.41) | MEN1KMT2ACHRNA7TSHR | |
| SCHEMBL2574686 | 0.64 | CHRNA7 (0.50) | MEN1KMT2AGAACHRNA7HTR3E | |
| SCHEMBL12127600 | 0.63 | KMT2A (0.52) | MEN1KMT2AGAACHRNA7HTR3E | |
| SCHEMBL4809454 | 0.63 | MEN1 (0.46) | MEN1KMT2AGAACHRNA7HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023178133-A9 | COMPOUNDS AND METHODS FOR TREATING DISEASE | ROME THERAPEUTICS, INC. (US) | 2023-10-26 | — | — | WO | disclosed |