SCHEMBL2574686

SCHEMBL2574686

O=C(OC1CCO1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 2/20 0.50
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
HTR3E A5X5Y0 1/20 0.47
HTR3B O95264 1/20 0.47
HTR3A P46098 1/20 0.47
HTR3D Q70Z44 1/20 0.47
HTR3C Q8WXA8 1/20 0.47
F2 P00734 1/20 0.47
LMNA P02545 1/20 0.47
BCHE P06276 2/20 0.47
APOBEC3A P31941 1/20 0.46
APOBEC3G Q9HC16 1/20 0.46
GAA P10253 1/20 0.45
TRPM8 Q7Z2W7 1/20 0.44
SLC18A3 Q16572 1/20 0.44
CHRM2 P08172 2/20 0.44
CHRM4 P08173 2/20 0.44
CHRM1 P11229 2/20 0.44
CHRM3 P20309 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11061705 0.91 SLC18A3 (0.48) CHRNA7MEN1KMT2AHTR3EHTR3B
SCHEMBL2573684 0.90 POLB (0.43) CHRNA7LMNA
SCHEMBL23817377 0.90 SLC18A3 (0.50) CHRNA7MEN1KMT2AHTR3EHTR3B
SCHEMBL2568781 0.87 KMT2A (0.41) CHRNA7KMT2ABCHETSHR
SCHEMBL10338863 0.85 BCHE (0.53) CHRNA7MEN1KMT2AHTR3EHTR3B
SCHEMBL10995636 0.83 BCHE (0.51) CHRNA7MEN1KMT2AHTR3EHTR3B
SCHEMBL2574276 0.83 KDM4E (0.40) BCHETSHR
SCHEMBL11245395 0.83 BCHE (0.46) CHRNA7MEN1KMT2AHTR3EHTR3B
SCHEMBL27544283 0.82 SCN1A (0.54) MEN1KMT2ALMNAGAA
SCHEMBL1648492 0.81 RAB9A (0.47) MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240067776-A1 METHOD FOR PREPARING POLYETHER CARBONATES ECONIC TECHNOLOGIES LTD (GB) 2024-02-29 US disclosed
US-20230033621-A1 A POLYOL BLOCK COPOLYMER ECONIC TECHNOLOGIES LTD. (GB) 2023-02-02 US disclosed
US-20220185956-A1 METHOD FOR QUENCHING A POLYMERISATION PROCESS ECONIC TECHNOLOGIES LTD (GB) 2022-06-16 US disclosed
WO-2021018085-A1 PREPARATION METHOD FOR HEXAHYDROFUROFURANOL DERIVATIVE, AND INTERMEDIATE OF THE DERIVATIVE AND PREPARATION METHOD THEREFOR 浙江九洲药业股份有限公司 2021-02-04 WO disclosed
US-20200369829-A1 METHOD FOR PREPARING POLYOLS ECONIC TECHNOLOGIES LTD. (GB) 2020-11-26 US disclosed
US-10774180-B2 Catalysts ECONIC TECHNOLOGIES LTD. (GB) 2020-09-15 US disclosed
US-10774179-B2 Method for preparing polyols ECONIC TECHNOLOGIES LTD. (GB) 2020-09-15 US disclosed
US-10556988-B2 Catalysts ECONIC TECHNOLOGIES LTD (GB) 2020-02-11 US disclosed
US-20190055352-A1 CATALYSTS ECONIC TECHNOLOGIES LTD. (GB) 2019-02-21 US disclosed
US-20180148539-A1 METHOD FOR PREPARING POLYOLS ECONIC TECHNOLOGIES LTD. (GB) 2018-05-31 US disclosed
US-20170210848-A1 Catalysts ECONIC TECHNOLOGIES LTD (GB) 2017-07-27 US disclosed
EP-1466946-B1 FLAME-RETARDANT RESIN COMPOSITION POLYPLASTICS CO (JP) 2011-11-09 EP disclosed
EP-1466946-A1 FLAME-RETARDANT RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2004-10-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10774180-B2 Catalysts CA1, CA12, CA4 CHRNA7 2105/4885MEN1 290/4885KMT2A 2911/4885
US-20190055352-A1 CATALYSTS CA1, CA12, CA4 CHRNA7 2105/4885MEN1 290/4885KMT2A 2911/4885
US-20170210848-A1 Catalysts MLX, CA3, CA1 CHRNA7 919/4885MEN1 2229/4885KMT2A 1627/4885
US-10556988-B2 Catalysts MLX, CA3, CA1 CHRNA7 919/4885MEN1 2229/4885KMT2A 1627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.