Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 5/20 | 0.45 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 3/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28372595 | 0.88 | AKR1C3 (0.43) | CTSADHODHFFAR1RXRARXRB | |
| SCHEMBL30541447 | 0.88 | AKR1C3 (0.43) | CTSADHODHFFAR1RXRARXRB | |
| SCHEMBL20545597 | 0.87 | CTSA (0.52) | CTSASLC13A5DHODHMMEFFAR1 | |
| SCHEMBL20545598 | 0.87 | CTSA (0.52) | CTSASLC13A5DHODHMMEFFAR1 | |
| SCHEMBL30671377 | 0.86 | CTSA (0.48) | CTSASLC13A5MMEPOLBFFAR1 | |
| SCHEMBL28368304 | 0.84 | CTSA (0.39) | CTSA | |
| SCHEMBL28373927 | 0.84 | ACLY (0.44) | DHODHFFAR1RXRARXRB | |
| SCHEMBL30541328 | 0.84 | ACLY (0.44) | DHODHFFAR1RXRARXRB | |
| SCHEMBL30671485 | 0.83 | CTSA (0.55) | CTSASLC13A5DHODHMMEPOLB | |
| SCHEMBL30541479 | 0.82 | CTSA (0.45) | CTSASLC13A5DHODHMMEPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3615514-B1 | PROPIONIC ACID DERIVATIVES AND METHODS OF USE THEREOF | AVIARA PHARMACEUTICALS INC (US) | 2023-11-22 | — | — | EP | disclosed |