Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28373927 | 1.00 | ACLY (0.44) | ACLYFFAR1ALDH1A1TSHRSLC1A3 | |
| SCHEMBL28368304 | 0.90 | CTSA (0.39) | ACLYALDH1A1MMEL1 | |
| SCHEMBL30541447 | 0.87 | AKR1C3 (0.43) | FFAR1ALDH1A1TSHRRXRARXRB | |
| SCHEMBL28372595 | 0.87 | AKR1C3 (0.43) | FFAR1ALDH1A1TSHRRXRARXRB | |
| SCHEMBL30541463 | 0.86 | FFAR1 (0.38) | FFAR1ALDH1A1TSHR | |
| SCHEMBL30671435 | 0.84 | CTSA (0.45) | FFAR1RXRARXRBDHODH | |
| SCHEMBL20545648 | 0.84 | FFAR1 (0.51) | ACLYFFAR1TSHRSLC1A3SLC1A2 | |
| SCHEMBL20545647 | 0.84 | FFAR1 (0.51) | ACLYFFAR1TSHRSLC1A3SLC1A2 | |
| SCHEMBL28368458 | 0.84 | CTSA (0.49) | — | |
| SCHEMBL30541339 | 0.84 | CTSA (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3615514-B1 | PROPIONIC ACID DERIVATIVES AND METHODS OF USE THEREOF | AVIARA PHARMACEUTICALS INC (US) | 2023-11-22 | — | — | EP | disclosed |
| CN-110914242-B | Propionic acid derivatives and methods of use thereof | 阿维亚拉药品有限公司 | 2023-07-25 | — | — | CN | disclosed |