Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 8/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3296787 | 0.82 | TRPA1 (0.46) | AOC3LMNAALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL9841040 | 0.79 | KDM4E (0.58) | AOC3LMNAKDM4EALDH1A1SLC6A2 | |
| SCHEMBL2636610 | 0.79 | KDM4E (0.58) | AOC3LMNAKDM4EALDH1A1SLC6A2 | |
| SCHEMBL2636608 | 0.79 | KDM4E (0.58) | AOC3LMNAKDM4EALDH1A1SLC6A2 | |
| SCHEMBL6577786 | 0.78 | AOC3 (0.73) | AOC3LMNAKDM4EALDH1A1SLC6A2 | |
| SCHEMBL15743820 | 0.78 | AOC3 (0.73) | AOC3LMNAKDM4EALDH1A1SLC6A2 | |
| SCHEMBL4367574 | 0.78 | LMNA (0.45) | LMNAALDH1A1ADRA2AKCNH2TRPA1 | |
| SCHEMBL4365709 | 0.78 | LMNA (0.45) | LMNAALDH1A1ADRA2AKCNH2TRPA1 | |
| SCHEMBL4369852 | 0.77 | TSHR (0.43) | AOC3LMNAKDM4EALDH1A1TRPA1 | |
| SCHEMBL14491043 | 0.76 | TRPA1 (0.56) | LMNAALDH1A1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160162-B | Asymmetric hydrogenation method of alpha-amino beta-keto ester | 南方科技大学 | 2023-11-28 | — | — | CN | disclosed |