Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21100002 | 0.86 | PDK1 (0.49) | ABCB1HTTPOLBPARP1FKBP1A | |
| SCHEMBL30672177 | 0.85 | NR1H2 (0.46) | ABCB1HTTPOLBPARP1FKBP1A | |
| SCHEMBL29121558 | 0.85 | ABCB1 (0.42) | ABCB1HTTPOLBPARP1FKBP1A | |
| SCHEMBL30672182 | 0.85 | NR1H2 (0.45) | ABCB1HTTPOLBPARP1FKBP1A | |
| SCHEMBL1864842 | 0.83 | POLB (0.52) | HTTPOLBFKBP1ANPSR1MITF | |
| SCHEMBL7802196 | 0.83 | POLB (0.52) | HTTPOLBFKBP1ANPSR1MITF | |
| SCHEMBL2300448 | 0.83 | POLB (0.52) | HTTPOLBFKBP1ANPSR1MITF | |
| SCHEMBL8332542 | 0.82 | FKBP1A (0.51) | ABCB1PARP1FKBP1APDK1PDK2 | |
| SCHEMBL17893034 | 0.82 | FKBP1A (0.51) | ABCB1PARP1FKBP1APDK1PDK2 | |
| SCHEMBL17896181 | 0.82 | FKBP1A (0.51) | ABCB1PARP1FKBP1APDK1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117222654-A | KRAS G12C inhibitors and uses thereof | 苏州赞荣医药科技有限公司 | 2023-12-12 | — | — | CN | disclosed |