Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | FES | P07332 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30672992 | 0.85 | FPR2 (0.55) | CNR1MEN1KMT2APOLBHTT | |
| SCHEMBL30672941 | 0.85 | CNR1 (0.53) | CNR1MEN1KMT2AHTTFES | |
| SCHEMBL30672985 | 0.84 | CNR1 (0.56) | CNR1MEN1KMT2APOLBFES | |
| SCHEMBL7790532 | 0.84 | CNR1 (0.67) | CNR1MEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL30673017 | 0.83 | TBXA2R (0.47) | CNR1MEN1KMT2AFESFGFR1 | |
| SCHEMBL30673046 | 0.82 | CNR1 (0.56) | CNR1MEN1KMT2AFESFGFR1 | |
| SCHEMBL30672916 | 0.81 | CNR1 (0.58) | CNR1MEN1KMT2AFESFGFR1 | |
| SCHEMBL30673004 | 0.81 | MEN1 (0.62) | CNR1MEN1KMT2APOLBFES | |
| SCHEMBL4362297 | 0.80 | FLT4 (0.60) | MEN1KMT2APOLBCHRM2CHRM1 | |
| SCHEMBL27249149 | 0.79 | AURKB (0.58) | CNR1MEN1KMT2AFESFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4532463-A1 | SQUARAMIDE DERIVATIVES AS CB1 ALLOSTERIC MODULATORS | Research Triangle Institute (US) | 2025-04-09 | — | — | EP | claimed |
| CN-119325464-A | Square amide derivatives as CB1 allosteric modulators | 研究三角协会 | 2025-01-17 | — | — | CN | claimed |
| WO-2023235548-A1 | SQUARAMIDE DERIVATIVES AS CB1 ALLOSTERIC MODULATORS | RESEARCH TRIANGLE INSTITUTE (US) | 2023-12-07 | — | — | WO | claimed |
| EP-4532463-A1 | SQUARAMIDE DERIVATIVES AS CB1 ALLOSTERIC MODULATORS | Research Triangle Institute (US) | 2025-04-09 | — | — | EP | disclosed |
| CN-119325464-A | Square amide derivatives as CB1 allosteric modulators | 研究三角协会 | 2025-01-17 | — | — | CN | disclosed |
| WO-2023235548-A1 | SQUARAMIDE DERIVATIVES AS CB1 ALLOSTERIC MODULATORS | RESEARCH TRIANGLE INSTITUTE (US) | 2023-12-07 | — | — | WO | disclosed |