Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 2/20 | 0.71 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.56 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.55 |
| ▸ | PTGES | O14684 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.48 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.48 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24172760 | 1.00 | FGFR4 (0.71) | FGFR4MAPKAPK2GAATRPV1EGLN1 | |
| SCHEMBL3043442 | 0.84 | EGLN1 (0.76) | TRPV1EGLN1PTGS1NPC1RAB9A | |
| SCHEMBL18070906 | 0.84 | TRPV1 (0.59) | FGFR4MAPKAPK2GAATRPV1PTGES | |
| SCHEMBL3140634 | 0.79 | MAPT (0.67) | EGLN1PTGS1NPC1RAB9ACASP3 | |
| SCHEMBL29863092 | 0.79 | MEN1 (0.63) | GAANPC1RAB9ACASP3SENP8 | |
| SCHEMBL31665119 | 0.77 | PTGS1 (0.65) | FGFR4MAPKAPK2GAATRPV1PTGES | |
| SCHEMBL25143580 | 0.77 | PTGS1 (0.65) | FGFR4MAPKAPK2GAATRPV1PTGES | |
| SCHEMBL28108390 | 0.76 | PARP1 (0.58) | EGLN1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL1031023 | 0.75 | FGFR4 (0.55) | FGFR4MAPKAPK2GAATRPV1EGLN1 | |
| SCHEMBL16762090 | 0.75 | TRPV1 (0.58) | FGFR4MAPKAPK2GAATRPV1PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4306524-A2 | LYMPHATIC SYSTEM-DIRECTING LIPID PRODRUGS | PureTech LYT, Inc. (US) | 2024-01-17 | — | — | EP | disclosed |