Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.60 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7686886 | 0.88 | EGLN1 (0.77) | MAPTKMT2AMEN1P2RX1RXFP1 | |
| SCHEMBL3043442 | 0.87 | EGLN1 (0.76) | MAPTKMT2AMEN1NPC1PTGS1 | |
| SCHEMBL23847684 | 0.85 | P2RX1 (0.67) | MAPTKMT2AMEN1P2RX1PTGS1 | |
| SCHEMBL3113627 | 0.84 | PTGS1 (0.68) | MAPTKMT2AMEN1P2RX1PTGS1 | |
| SCHEMBL3110003 | 0.84 | KMT2A (0.65) | MAPTKMT2AMEN1P2RX1PTGS1 | |
| SCHEMBL3041133 | 0.81 | NPC1 (0.76) | MAPTKMT2AMEN1NPC1CASP3 | |
| SCHEMBL27652617 | 0.79 | RXFP1 (0.88) | MAPTP2RX1PTGS1RXFP1 | |
| SCHEMBL30674279 | 0.79 | FGFR4 (0.71) | KMT2AMEN1NPC1PTGS1CASP3 | |
| SCHEMBL24172760 | 0.79 | FGFR4 (0.71) | KMT2AMEN1NPC1PTGS1CASP3 | |
| SCHEMBL8311076 | 0.78 | EGLN1 (0.80) | MAPTP2RX1ALDH1A1EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247622-A1 | TREATMENT REGIME FOR PROLIFERATIVE DISORDERS | ONCOLYTICS BIOTECH INC. (CA) | 2010-09-30 | — | — | US | disclosed |
| CN-101820892-A | Treatment regime for proliferative disorders | ONCOLYTICS BIOTECH INC | 2010-09-01 | — | — | CN | disclosed |
| WO-2009052617-A9 | TREATMENT REGIME FOR PROLIFERATIVE DISORDERS | ONCOLYTICS BIOTECH INC. (CA) | 2010-08-05 | — | — | WO | disclosed |
| EP-2211880-A1 | TREATMENT REGIME FOR PROLIFERATIVE DISORDERS | Oncolytics Biotech Inc. (CA) | 2010-08-04 | — | — | EP | disclosed |
| WO-2009052617-A1 | TREATMENT REGIME FOR PROLIFERATIVE DISORDERS | ONCOLYTICS BIOTECH INC. (CA) | 2009-04-30 | — | — | WO | disclosed |