SCHEMBL1031023

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1033871	0.90	FGFR4 (0.51)	FGFR4MAPKAPK2EGLN1CHRNB2CHRNB4
	SCHEMBL1034318	0.88	FGFR4 (0.53)	FGFR4MAPKAPK2EGLN1TRPV1CHRNB2
	SCHEMBL1033965	0.83	CHRNB2 (0.52)	FGFR4MAPKAPK2TRPV1CHRNB2CHRNB4
	SCHEMBL1031026	0.82	ATR (0.57)	EGLN1CHRNB2CHRNB4CHRNA3CHRNA4
	SCHEMBL1033554	0.81	SCN9A (0.53)	FGFR4MAPKAPK2EGLN1SIRT2NPC1
	SCHEMBL1036232	0.81	SIRT2 (0.50)	FGFR4MAPKAPK2CHRNB2CHRNB4CHRNA3
	SCHEMBL1034553	0.80	EPHX2 (0.54)	FGFR4MAPKAPK2EGLN1SIRT2NPC1
	SCHEMBL1076631	0.78	PARP1 (0.56)	FGFR4MAPKAPK2KDM4EPARP1TP53
	SCHEMBL1035234	0.78	MPL (0.52)	FGFR4MAPKAPK2EGLN1CHRNB2CHRNB4
	SCHEMBL1034603	0.78	ALOX15 (0.59)	FGFR4MAPKAPK2SIRT2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.