Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 16/20 | 0.52 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.49 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.48 |
| ▸ | CLK2 | P49760 | 3/20 | 0.46 |
| ▸ | CLK3 | P49761 | 3/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.46 |
| ▸ | WNT1 | P04628 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1780991 | 0.79 | CYP19A1 (0.66) | RIPK1CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL26503311 | 0.76 | PIK3C3 (0.48) | CCNB2CDK1CCNB1CCNB3NPY5R | |
| SCHEMBL20765188 | 0.76 | PIK3C3 (0.48) | CCNB2CDK1CCNB1CCNB3NPY5R | |
| SCHEMBL30380842 | 0.76 | PIK3C3 (0.48) | CCNB2CDK1CCNB1CCNB3NPY5R | |
| SCHEMBL26053438 | 0.75 | RIPK1 (0.71) | RIPK1CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL1778505 | 0.73 | RIPK1 (0.74) | RIPK1CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL7892114 | 0.72 | RIPK1 (0.71) | RIPK1CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL14733052 | 0.70 | ULK1 (0.53) | CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL28300252 | 0.70 | RIPK1 (0.62) | RIPK1CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL21755111 | 0.70 | RIPK1 (0.53) | RIPK1CCNB2CDK1CCNB1CCNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117241800-A | Antiviral Activity of VPS34 inhibitors | 德西费拉制药有限责任公司 | 2023-12-15 | — | — | CN | claimed |