Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 13/20 | 0.48 |
| ▸ | MAPT | P10636 | 12/20 | 0.48 |
| ▸ | RAB9A | P51151 | 11/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 8/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31576451 | 1.00 | NPC1 (0.48) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL8484610 | 0.86 | MAPT (0.51) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL8484614 | 0.86 | MAPT (0.51) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL30677376 | 0.82 | NPC1 (0.51) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL8481591 | 0.81 | NPC1 (0.55) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL30677280 | 0.81 | MAPT (0.52) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL31576447 | 0.81 | MAPT (0.52) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL30676759 | 0.79 | MAPT (0.61) | MAPTKDM4ELMNAHPGDALDH1A1 | |
| SCHEMBL31576473 | 0.79 | MAPT (0.61) | MAPTKDM4ELMNAHPGDALDH1A1 | |
| SCHEMBL8484763 | 0.79 | RAB9A (0.53) | NPC1MAPTRAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024014885-A1 | NOVEL BICYCLIC HETEROARYL COMPOUND AND USE THEREOF | 일동제약(주) | 2024-01-18 | — | — | WO | disclosed |