Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.53 |
| ▸ | NPC1 | O15118 | 9/20 | 0.53 |
| ▸ | GAA | P10253 | 6/20 | 0.53 |
| ▸ | PKM | P14618 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CTH | P32929 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8481591 | 0.90 | NPC1 (0.55) | RAB9ANPC1GAAPKMSMN1; SMN2 | |
| SCHEMBL8480872 | 0.88 | RAB9A (0.53) | RAB9ANPC1GAAPKMSMN1; SMN2 | |
| SCHEMBL8484610 | 0.87 | MAPT (0.51) | RAB9ANPC1GAAPKMSMN1; SMN2 | |
| SCHEMBL8484614 | 0.87 | MAPT (0.51) | RAB9ANPC1GAAPKMSMN1; SMN2 | |
| SCHEMBL8487763 | 0.84 | NOX3 (0.51) | RAB9ANPC1GAAPKMSMN1; SMN2 | |
| SCHEMBL8480596 | 0.84 | MAPT (0.56) | RAB9ANPC1GAAPKMSMN1; SMN2 | |
| SCHEMBL8484425 | 0.82 | MAPT (0.48) | RAB9ANPC1GAAPKMSMN1; SMN2 | |
| SCHEMBL31576451 | 0.79 | NPC1 (0.48) | RAB9ANPC1GAAPKMSMN1; SMN2 | |
| SCHEMBL30677381 | 0.79 | NPC1 (0.48) | RAB9ANPC1GAAPKMSMN1; SMN2 | |
| SCHEMBL8484488 | 0.78 | NPC1 (0.50) | RAB9ANPC1GAAPKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5990118-A | NOVEL PURINE COMPOUNDS AND TRIAZOLOPURINE COMPOUNDS WHICH INHIBIT XANTHINE OXIDASE; REMEDIES FOR HYPERURICEMIA, AND AS PREVENTIVE AND THERAPEUTIC AGENTS FOR GOUT | YAMASA CORPORATION (JP) | 1999-11-23 | — | — | US | disclosed |
| EP-0811624-A1 | PURINE COMPOUNDS AND XANTHINE OXIDASE INHIBITORS | YAMASA CORPORATION (JP) | 1997-12-10 | — | — | EP | disclosed |