Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 3/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.40 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | CBFB | Q13951 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30677309 | 0.76 | PIK3CA (0.43) | PIK3CAPIK3CDPIK3CBTP53KMT2A | |
| SCHEMBL497431 | 0.72 | DCTPP1 (0.48) | PIK3CAPIK3CDPIK3CBTP53KMT2A | |
| SCHEMBL4035898 | 0.71 | TSHR (0.42) | PIK3CAPIK3CDPIK3CBTP53KMT2A | |
| SCHEMBL14334321 | 0.68 | KMT2A (0.42) | PIK3CAPIK3CDPIK3CBTP53KMT2A | |
| SCHEMBL21325364 | 0.68 | CNR1 (0.43) | PIK3CATP53KMT2AMEN1TSHR | |
| SCHEMBL15893927 | 0.68 | CYP2C19 (0.43) | PIK3CAPIK3CBTP53KMT2AMEN1 | |
| SCHEMBL30766045 | 0.67 | KMT2A (0.51) | PIK3CATP53KMT2AMEN1TSHR | |
| SCHEMBL15733180 | 0.66 | HTT (0.47) | PIK3CATP53KMT2AMEN1TSHR | |
| SCHEMBL9760977 | 0.66 | POLB (0.52) | TP53KMT2AMEN1TSHRHSD17B10 | |
| SCHEMBL14334236 | 0.66 | KMT2A (0.43) | TP53KMT2AMEN1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024014885-A1 | NOVEL BICYCLIC HETEROARYL COMPOUND AND USE THEREOF | 일동제약(주) | 2024-01-18 | — | — | WO | disclosed |