Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13729176 | 0.73 | POLB (0.48) | POLBALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL14334321 | 0.71 | KMT2A (0.42) | POLBALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL9761124 | 0.71 | KMT2A (0.52) | ALDH1A1CYP1A2CYP2C9MAPTCYP2C19 | |
| SCHEMBL30766045 | 0.70 | KMT2A (0.51) | POLBALDH1A1MAPTMEN1TSHR | |
| SCHEMBL3386200 | 0.69 | ALDH1A1 (0.65) | POLBALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL14334236 | 0.69 | KMT2A (0.43) | POLBALDH1A1MAPTHTTMEN1 | |
| SCHEMBL29437404 | 0.69 | POLB (1.00) | POLBALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL15733180 | 0.69 | HTT (0.47) | POLBALDH1A1HTTMEN1TSHR | |
| SCHEMBL9762614 | 0.69 | POLB (0.49) | POLBALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL9762559 | 0.69 | ALDH1A1 (0.49) | POLBALDH1A1CYP1A2CYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |