Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 16/20 | 0.63 |
| ▸ | BCL2 | P10415 | 2/20 | 0.63 |
| ▸ | ALB | P02768 | 1/20 | 0.63 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 2/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | HTR1D | P28221 | 1/20 | 0.54 |
| ▸ | HTR1B | P28222 | 1/20 | 0.54 |
| ▸ | HTR1F | P30939 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2202505 | 0.91 | MCL1 (0.76) | MCL1BCL2ALBBCL2L1HTR6 | |
| SCHEMBL30679056 | 0.91 | MCL1 (0.76) | MCL1BCL2ALBBCL2L1HTR6 | |
| SCHEMBL22436900 | 0.90 | MCL1 (0.66) | MCL1BCL2ALBBCL2L1 | |
| SCHEMBL29928106 | 0.88 | MCL1 (0.82) | MCL1BCL2ALBBCL2L1 | |
| SCHEMBL15622375 | 0.86 | MCL1 (0.70) | MCL1BCL2ALBBCL2L1HTR6 | |
| SCHEMBL2205702 | 0.86 | HTR6 (0.60) | MCL1BCL2ALBBCL2L1HTR6 | |
| SCHEMBL30679060 | 0.85 | MCL1 (0.79) | MCL1BCL2ALBBCL2L1 | |
| SCHEMBL2204455 | 0.85 | MCL1 (0.71) | MCL1BCL2ALBBCL2L1HTR6 | |
| SCHEMBL15622777 | 0.84 | MCL1 (0.73) | MCL1BCL2ALBBCL2L1HTR6 | |
| SCHEMBL22436687 | 0.83 | MCL1 (0.47) | MCL1BCL2ALBBCL2L1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111757884-B | Substituted macrocyclic indole derivatives | 拜耳股份公司 | 2023-12-19 | — | — | CN | disclosed |