Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29521535 | 0.87 | MEN1 (0.49) | NPC1LMNAALDH1A1HTTHPGD | |
| SCHEMBL29385536 | 0.86 | KMT2A (0.43) | NPC1LMNAALDH1A1HTTHPGD | |
| SCHEMBL28191790 | 0.85 | NPC1 (0.39) | NPC1ALDH1A1HTTHPGDSMN1; SMN2 | |
| SCHEMBL8752790 | 0.85 | NPC1 (0.41) | NPC1LMNAHPGDSMN1; SMN2MEN1 | |
| SCHEMBL28069714 | 0.82 | FABP5 (0.45) | NPC1LMNAALDH1A1HTTHPGD | |
| SCHEMBL6298097 | 0.82 | FABP5 (0.41) | LMNAALDH1A1HTTSMN1; SMN2GAA | |
| SCHEMBL31013146 | 0.81 | KMT2A (0.34) | NPC1LMNAHTTSMN1; SMN2MEN1 | |
| SCHEMBL3485726 | 0.81 | FABP5 (0.41) | NPC1ALDH1A1HTTGAAMEN1 | |
| SCHEMBL27082137 | 0.81 | NPC1 (0.40) | NPC1LMNAALDH1A1HTTHPGD | |
| SCHEMBL20973955 | 0.80 | NPC1 (0.40) | NPC1LMNAALDH1A1HTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110267971-B | Immunomodulators | 百时美施贵宝公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-110536696-B | PCSK9 vaccine based on novel peptides | 载度思生命科学有限公司 | 2023-11-24 | — | — | CN | disclosed |