Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP5 | Q01469 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28069714 | 0.93 | FABP5 (0.45) | FABP5EPHX2KMT2ATSHRMEN1 | |
| SCHEMBL28191790 | 0.89 | NPC1 (0.39) | FABP5KMT2ATSHRMEN1GPR55 | |
| SCHEMBL6298097 | 0.89 | FABP5 (0.41) | FABP5KMT2ATSHRMEN1GPR55 | |
| SCHEMBL8752790 | 0.89 | NPC1 (0.41) | FABP5KMT2ATSHRMEN1GPR55 | |
| SCHEMBL30679137 | 0.81 | NPC1 (0.44) | KMT2AMEN1HTTALDH1A1GAA | |
| SCHEMBL29385536 | 0.81 | KMT2A (0.43) | FABP5KMT2ATSHRMEN1GPR55 | |
| SCHEMBL31013146 | 0.81 | KMT2A (0.34) | FABP5KMT2ATSHRMEN1GPR55 | |
| SCHEMBL29521535 | 0.80 | MEN1 (0.49) | KMT2ATSHRMEN1GPR55HTT | |
| SCHEMBL27082137 | 0.80 | NPC1 (0.40) | FABP5KMT2ATSHRMEN1GPR55 | |
| SCHEMBL7867953 | 0.80 | FABP5 (0.39) | FABP5KMT2AGAAFABP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140031523-A1 | Selective Poly-N-Substituted Glycine Antibiotics | BARRON ANNELISE E (US) | 2014-01-30 | — | — | US | disclosed |
| US-8445632-B2 | Selective poly-N-substituted glycine antibiotics | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-05-21 | — | — | US | disclosed |
| US-20120295838-A1 | Selective poly-substituted glycine antibiotics and related compositions | BARRON ANNELISE E (US) | 2012-11-22 | — | — | US | disclosed |
| EP-2252576-A2 | SELECTIVE POLY-N-SUBSTITUTED GLYCINE ANTIBIOTICS | Northwestern University (US) | 2010-11-24 | — | — | EP | disclosed |
| US-20100036088-A1 | Selective poly-N-substituted glycine antibiotics | CHONGSIRIWATANA, NATHANIEL P. | 2010-02-11 | — | — | US | disclosed |
| WO-2009105167-A2 | SELECTIVE POLY-N-SUBSTITUTED GLYCINE ANTIBIOTICS | NORTHWESTERN UNIVERSITY (US) | 2009-08-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100036088-A1 | Selective poly-N-substituted glycine antibiotics | PARG, PAM, NGLY1 | FABP5 2411/4885EPHX2 4718/4885KMT2A 3272/4885 |
| US-20140031523-A1 | Selective Poly-N-Substituted Glycine Antibiotics | PARG, PAM, NGLY1 | FABP5 2411/4885EPHX2 4718/4885KMT2A 3272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.