Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 6/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.39 |
| ▸ | FEN1 | P39748 | 2/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | MPL | P40238 | 2/20 | 0.37 |
| ▸ | KMO | O15229 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30679635 | 0.80 | CYP11B1 (0.43) | PTPN1ERN1CYP11B1CYP11B2KIF11 | |
| SCHEMBL30679661 | 0.77 | PTPN1 (0.44) | PTPN1ALOX5APFEN1 | |
| SCHEMBL5156136 | 0.77 | ESR1 (0.52) | ERN1 | |
| SCHEMBL3245477 | 0.74 | PIM1 (0.42) | PTPN1ERN1KIF11 | |
| SCHEMBL5150260 | 0.73 | ERN1 (0.54) | ERN1 | |
| SCHEMBL485577 | 0.72 | ERN1 (0.47) | ERN1 | |
| SCHEMBL29951202 | 0.72 | ERN1 (0.47) | ERN1 | |
| SCHEMBL30679633 | 0.71 | TDP1 (0.43) | PTPN1ERN1 | |
| SCHEMBL14580133 | 0.71 | ALDH1A1 (0.43) | ERN1 | |
| SCHEMBL28066001 | 0.71 | BACE1 (0.52) | ERN1ALOX5APFEN1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430570-A | Rhodamine acetic acid compound, and pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-01-23 | — | — | CN | disclosed |