Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL485577 | 1.00 | ERN1 (0.47) | ERN1MEN1KMT2ALMNATHRB | |
| Hydrochloric Acid SCHEMBL28960226 | 0.98 | ERN1 (0.45) | ERN1MEN1KMT2ALMNATHRB | |
| SCHEMBL9671258 | 0.86 | ERN1 (0.57) | ERN1MEN1KMT2ALMNATHRB | |
| SCHEMBL12143561 | 0.86 | ERN1 (0.57) | ERN1MEN1KMT2ALMNATHRB | |
| SCHEMBL982388 | 0.85 | KMT2A (0.61) | MEN1KMT2ALMNATHRBBLM | |
| SCHEMBL29786760 | 0.85 | KMT2A (0.61) | MEN1KMT2ALMNATHRBBLM | |
| SCHEMBL6757215 | 0.77 | ALDH1A1 (0.38) | LMNAALDH1A1HTTKDM4ENPSR1 | |
| SCHEMBL13747587 | 0.77 | NFE2L2 (0.36) | LMNAALDH1A1HTTKDM4ENPSR1 | |
| SCHEMBL31596866 | 0.77 | ALDH1A1 (0.38) | LMNAALDH1A1HTTKDM4ENPSR1 | |
| SCHEMBL6562728 | 0.77 | HPRT1 (0.46) | LMNATDP1CYP2A6ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |