SCHEMBL30679648

SCHEMBL30679648

O=Cc1ccc(-c2cccc(Cl)c2)cn1

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.47
EGLN1 Q9GZT9 1/20 0.46
F2R P25116 12/20 0.45
ALOX5 P09917 1/20 0.43
NFE2L2 Q16236 1/20 0.42
MAP4K4 O95819 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5247452 1.00 CNR2 (0.47) CNR2EGLN1F2RALOX5NFE2L2
SCHEMBL2555787 0.81 F2R (0.49) F2RMAP4K4TAAR1
SCHEMBL4005376 0.80 LTA4H (0.43) EGLN1F2RNFE2L2MAP4K4NPC1
SCHEMBL12284810 0.80 F2R (0.46) EGLN1F2RMAP4K4
SCHEMBL26031105 0.80 HSD17B1 (0.60) MAP4K4
SCHEMBL29893944 0.80 KCNJ1 (0.44) NPC1RAB9ASMN1; SMN2
SCHEMBL30893537 0.80 KCNJ1 (0.44) NPC1RAB9ASMN1; SMN2
SCHEMBL16761877 0.80 KCNJ1 (0.44) NPC1RAB9ASMN1; SMN2
SCHEMBL1585273 0.78 NPC1 (0.45) F2RNPC1RAB9ASMN1; SMN2
SCHEMBL28778071 0.78 MAP4K4 (0.49) CNR2ALOX5NFE2L2MAP4K4TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117430570-A Rhodamine acetic acid compound, and pharmaceutical composition and application thereof 中国医学科学院药物研究所 2024-01-23 CN disclosed