SCHEMBL30680271

SCHEMBL30680271

CC(C)(C)OC(=O)c1ccccc1NC(=O)C(Cc1ccccc1)NC(=O)C(=O)Nc1c(-n2cnnn2)ccc(Cl)c1Cl

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F11 P03951 19/20 0.44
KLKB1 P03952 15/20 0.44
CTSL P07711 1/20 0.36
KLK1 P06870 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30680269 0.89 F11 (0.46) F11KLKB1
SCHEMBL23486605 0.89 F11 (0.51) F11KLKB1KLK1
SCHEMBL23486635 0.82 F11 (0.52) F11KLKB1
SCHEMBL30680262 0.82 F11 (0.46) F11KLKB1
SCHEMBL23486606 0.81 F11 (0.54) F11KLKB1KLK1
SCHEMBL29758159 0.77 F11 (0.42) F11KLKB1KLK1
SCHEMBL30680317 0.76 F11 (0.51) F11KLKB1KLK1
SCHEMBL30680284 0.76 KMT2A (0.49)
SCHEMBL30680256 0.76 CTSS (0.41) F11CTSL
SCHEMBL30680293 0.74 MEN1 (0.41) F11KLKB1CTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114728917-B Oxamide derivative, preparation method and medical application thereof 深圳信立泰药业股份有限公司 2023-12-08 CN disclosed