Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.34 |
| ▸ | ABL1 | P00519 | 7/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.30 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17381571 | 1.00 | NR1H4 (0.34) | NR1H4ABL1GPR119SCN9ASCN5A | |
| SCHEMBL17381580 | 0.96 | NR1H4 (0.34) | NR1H4ABL1GPR119GRM5SSTR2 | |
| SCHEMBL19321662 | 0.94 | NR1H4 (0.33) | NR1H4ABL1GPR119GRM5 | |
| SCHEMBL17382346 | 0.92 | ABL1 (0.33) | NR1H4ABL1GPR119SCN9A | |
| SCHEMBL19326492 | 0.90 | NR1H4 (0.33) | NR1H4ABL1GPR119GRM5 | |
| SCHEMBL23072074 | 0.89 | GPR119 (0.32) | NR1H4ABL1GPR119 | |
| SCHEMBL31236967 | 0.89 | ABL1 (0.33) | ABL1GPR119GRM5SSTR2 | |
| SCHEMBL17381637 | 0.89 | NR1H4 (0.35) | NR1H4GPBAR1 | |
| SCHEMBL17381595 | 0.89 | PTGDR2 (0.35) | NR1H4GRM5 | |
| SCHEMBL17381573 | 0.86 | NR1H4 (0.35) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3157929-B1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | ARES TRADING SA (CH) | 2023-12-13 | — | — | EP | disclosed |