Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 4/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17382346 | 0.96 | ABL1 (0.33) | GPR119ABL1RIPK1NR1H4 | |
| SCHEMBL29539087 | 0.95 | GPR119 (0.31) | GPR119ABL1CYP11B2RIPK1 | |
| SCHEMBL17381955 | 0.95 | GPR119 (0.31) | GPR119ABL1CYP11B2RIPK1 | |
| SCHEMBL19326927 | 0.93 | — | — | |
| SCHEMBL17381580 | 0.92 | NR1H4 (0.34) | GPR119ABL1RIPK1NR1H4 | |
| SCHEMBL17381571 | 0.89 | NR1H4 (0.34) | GPR119ABL1NR1H4 | |
| SCHEMBL30681665 | 0.89 | NR1H4 (0.34) | GPR119ABL1NR1H4 | |
| SCHEMBL17381651 | 0.88 | CCNA2 (0.32) | NR1H4 | |
| SCHEMBL17382363 | 0.87 | NR1H4 (0.33) | NR1H4 | |
| SCHEMBL31236967 | 0.85 | ABL1 (0.33) | GPR119ABL1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10941152-B2 | Pyrazole compounds as modulators of FSHR and uses thereof | ARES TRADING S.A. (CH) | 2021-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10941152-B2 | Pyrazole compounds as modulators of FSHR and uses thereof | FSHR, GNRHR, LHCGR | GPR119 29/4885ABL1 4391/4885CYP11B2 142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.