SCHEMBL30682124

SCHEMBL30682124

BrCc1ccnc2cncnc12

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 1/20 0.32
EGFR P00533 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10077306 0.81 CYP2C19 (0.33) LOXL2EGFR
SCHEMBL638191 0.73 LOXL2 (0.41) LOXL2EGFR
SCHEMBL30682143 0.73 KDM4C (0.42) LOXL2EGFR
SCHEMBL30682105 0.71 NR4A2 (0.35)
SCHEMBL30682114 0.71 HTT (0.37)
SCHEMBL23618577 0.71 EGFR (0.33) EGFR
SCHEMBL10200834 0.71 CCR1 (0.40) EGFR
SCHEMBL29237038 0.71 EGFR (0.33) EGFR
SCHEMBL30682141 0.71 CCR1 (0.40) EGFR
SCHEMBL10077933 0.70 RPS6KA3 (0.31) EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250360145-A1 CSF-1R INHIBITORS AND USES THEREOF MYROBALAN THERAPEUTICS INC (US) 2025-11-27 US disclosed
EP-4539933-A1 CSF-1R INHIBITORS AND USES THEREOF Myrobalan Therapeutics, Inc. (US) 2025-04-23 EP disclosed
CN-119790038-A CSF-1R inhibitors and uses thereof 迈巴制药公司 2025-04-08 CN disclosed
WO-2023241608-A1 CSF-1R INHIBITORS AND USES THEREOF MYROBALAN THERAPEUTICS NANJING CO. LTD (CN) 2023-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250360145-A1 CSF-1R INHIBITORS AND USES THEREOF CSF1R, CSF3R, IL1RN LOXL2 1962/4885EGFR 643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.