Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16955085 | 1.00 | NOS3 (0.46) | NOS3NOS1NOS2MAOBMAOA | |
| SCHEMBL31434232 | 0.84 | MAOB (0.40) | NOS3NOS1NOS2MAOBMAOA | |
| SCHEMBL307884 | 0.82 | NOS3 (0.47) | NOS3NOS1NOS2MAOBMAOA | |
| SCHEMBL1519547 | 0.80 | CSNK2A1 (0.49) | NOS3NOS1NOS2MAOBMAOA | |
| SCHEMBL12317793 | 0.80 | NOS3 (0.46) | NOS3NOS1NOS2MAOBMAOA | |
| SCHEMBL1366457 | 0.80 | NOS3 (0.49) | NOS3NOS1NOS2MAOBMAOA | |
| SCHEMBL31256059 | 0.78 | NOS3 (0.44) | NOS3NOS1NOS2MAOBMAOA | |
| SCHEMBL16897461 | 0.78 | NOS3 (0.44) | NOS3NOS1NOS2MAOBMAOA | |
| SCHEMBL16961104 | 0.78 | CA2 (0.38) | PTGDR2 | |
| SCHEMBL13570672 | 0.77 | NOS3 (0.47) | NOS3NOS1NOS2MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023239645-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |