Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.41 |
| ▸ | TPSD1 | Q9BZJ3 | 3/20 | 0.41 |
| ▸ | TPSG1 | Q9NRR2 | 3/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30683053 | 1.00 | SYK (0.47) | SYKL3MBTL1MALT1IDO1MAPT | |
| SCHEMBL30683041 | 1.00 | SYK (0.47) | SYKL3MBTL1MALT1IDO1MAPT | |
| SCHEMBL26932017 | 1.00 | SYK (0.47) | SYKL3MBTL1MALT1IDO1MAPT | |
| SCHEMBL26931815 | 0.87 | MALT1 (0.49) | MALT1IDO1MEN1KMT2ATPSAB1 | |
| SCHEMBL26931811 | 0.87 | MALT1 (0.49) | MALT1IDO1MEN1KMT2ATPSAB1 | |
| SCHEMBL24838499 | 0.82 | ALDH1A1 (0.43) | L3MBTL1POLBCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL26932025 | 0.82 | ALDH1A1 (0.40) | SYKL3MBTL1POLB | |
| SCHEMBL30683055 | 0.82 | ALDH1A1 (0.40) | SYKL3MBTL1POLB | |
| SCHEMBL26960533 | 0.79 | SYK (0.54) | SYKL3MBTL1IDO1MAPTPOLB | |
| SCHEMBL26931772 | 0.79 | SYK (0.54) | SYKL3MBTL1IDO1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023239645-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |