Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26932025 | 1.00 | ALDH1A1 (0.40) | ALDH1A1GAACDC25BUSP2LMNA | |
| SCHEMBL24838501 | 0.88 | ALDH1A1 (0.44) | ALDH1A1GAAUSP2LMNAHTT | |
| SCHEMBL24838499 | 0.82 | ALDH1A1 (0.43) | ALDH1A1GAAUSP2LMNAHTT | |
| SCHEMBL30683053 | 0.82 | SYK (0.47) | SYKPOLBL3MBTL1 | |
| SCHEMBL30683047 | 0.82 | SYK (0.47) | SYKPOLBL3MBTL1 | |
| SCHEMBL30683041 | 0.82 | SYK (0.47) | SYKPOLBL3MBTL1 | |
| SCHEMBL26932017 | 0.82 | SYK (0.47) | SYKPOLBL3MBTL1 | |
| SCHEMBL30683090 | 0.81 | TDP1 (0.44) | ALDH1A1GAAUSP2LMNAHTT | |
| SCHEMBL24838500 | 0.81 | ALDH1A1 (0.42) | ALDH1A1GAAUSP2LMNAHTT | |
| SCHEMBL26932103 | 0.81 | TDP1 (0.44) | ALDH1A1GAAUSP2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023239645-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |