Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 5/20 | 0.35 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | ACVR2A | P27037 | 1/20 | 0.33 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20743017 | 1.00 | MAPK13 (0.39) | MAPK13MAPK12MAPK11MAPK14NLRP3 | |
| SCHEMBL30684090 | 0.90 | NLRP3 (0.42) | MAPK13MAPK12MAPK11MAPK14NLRP3 | |
| SCHEMBL20609769 | 0.90 | NLRP3 (0.42) | MAPK13MAPK12MAPK11MAPK14NLRP3 | |
| SCHEMBL30684162 | 0.81 | MYC (0.36) | NLRP3 | |
| SCHEMBL20609767 | 0.81 | MYC (0.36) | NLRP3 | |
| SCHEMBL29109512 | 0.81 | NLRP3 (0.37) | MAPK13MAPK12MAPK11MAPK14NLRP3 | |
| SCHEMBL20742969 | 0.79 | MAPK14 (0.42) | MAPK13MAPK12MAPK11MAPK14NLRP3 | |
| SCHEMBL30684129 | 0.79 | MAPK14 (0.42) | MAPK13MAPK12MAPK11MAPK14NLRP3 | |
| SCHEMBL25236267 | 0.79 | NLRP3 (0.41) | MAPK13MAPK12MAPK11MAPK14NLRP3 | |
| SCHEMBL30417670 | 0.79 | NLRP3 (0.41) | MAPK13MAPK12MAPK11MAPK14NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111132974-B | Sulfonamide carboxamide compounds | 英夫拉索姆有限公司 | 2023-11-21 | — | — | CN | disclosed |