Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 5/20 | 0.40 |
| ▸ | ACVR2A | P27037 | 2/20 | 0.36 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.35 |
| ▸ | FEN1 | P39748 | 5/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20742969 | 1.00 | MAPK14 (0.42) | MAPK14MAPK13MAPK12MAPK11NLRP3 | |
| SCHEMBL29927552 | 0.88 | NLRP3 (0.48) | MAPK14MAPK13MAPK12MAPK11NLRP3 | |
| SCHEMBL20609796 | 0.88 | NLRP3 (0.48) | MAPK14MAPK13MAPK12MAPK11NLRP3 | |
| SCHEMBL20744375 | 0.87 | NLRP3 (0.41) | MAPK14MAPK13MAPK12MAPK11NLRP3 | |
| SCHEMBL30684077 | 0.87 | NLRP3 (0.41) | MAPK14MAPK13MAPK12MAPK11NLRP3 | |
| SCHEMBL23012692 | 0.82 | ADORA2B (0.43) | MAPK14MAPK13MAPK12MAPK11NLRP3 | |
| SCHEMBL20744447 | 0.82 | DYRK1A (0.39) | MAPK14MAPK13MAPK12MAPK11NLRP3 | |
| SCHEMBL29573583 | 0.82 | ADORA2B (0.43) | MAPK14MAPK13MAPK12MAPK11NLRP3 | |
| SCHEMBL20743706 | 0.81 | TDO2 (0.39) | HRH4PIK3CB | |
| SCHEMBL30684113 | 0.81 | TDO2 (0.39) | HRH4PIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111132974-B | Sulfonamide carboxamide compounds | 英夫拉索姆有限公司 | 2023-11-21 | — | — | CN | disclosed |