Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.30 |
| ▸ | SELE | P16581 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26912459 | 0.80 | KDM4C (0.34) | KDM4CL3MBTL1NPC1RAB9AGRIN1 | |
| SCHEMBL26912577 | 0.79 | KDM4C (0.33) | KDM4CL3MBTL1NPC1RAB9AGRIN1 | |
| SCHEMBL31703050 | 0.75 | L3MBTL1 (0.43) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL17865660 | 0.73 | HRH4 (0.38) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL26913307 | 0.73 | CREBBP (0.36) | KDM4CNPC1RAB9AGRIN1MEN1 | |
| SCHEMBL26912200 | 0.73 | CGAS (0.39) | KDM4CL3MBTL1 | |
| SCHEMBL30684394 | 0.71 | CREBBP (0.34) | GRIN1MEN1KMT2AICAM1SELE | |
| SCHEMBL29746500 | 0.71 | KDM4C (0.36) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL29746437 | 0.70 | KMT2A (0.51) | KDM4CRAB9AMEN1KMT2AICAM1 | |
| SCHEMBL26913794 | 0.69 | KDM4C (0.33) | KDM4CL3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235809-A1 | CGAS INHIBITORS | ELI LILLY AND COMPANY (US) | 2023-12-07 | — | — | WO | disclosed |