Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 5/20 | 0.34 |
| ▸ | HTR3A | P46098 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30376189 | 0.80 | HTR3A (0.44) | HTR3AMAP4K4CHEK1ALDH1A1 | |
| SCHEMBL26698247 | 0.76 | MAPT (0.37) | ROCK1MAPTCYP3A4ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL30557207 | 0.73 | BIRC5 (0.49) | ROCK1HTR3AMAPTMAP4K4 | |
| SCHEMBL4880774 | 0.72 | ALDH1A1 (0.44) | ROCK1MAPTCYP3A4ALDH1A1HPGD | |
| SCHEMBL4878604 | 0.72 | MAPT (0.46) | ROCK1MAPTMKNK1MKNK2CYP3A4 | |
| SCHEMBL15910764 | 0.72 | SYK (0.41) | HTR3AMAPTDDB1CRBN | |
| Hydrochloric Acid SCHEMBL30376227 | 0.70 | AKT1 (0.34) | HTR3AMAPTMAP4K4CHEK1ALDH1A1 | |
| SCHEMBL3300423 | 0.69 | RPS6KA5 (0.53) | ROCK1MAPTMKNK1MKNK2CYP3A4 | |
| SCHEMBL29961184 | 0.69 | RPS6KA5 (0.53) | ROCK1MAPTMKNK1MKNK2CYP3A4 | |
| SCHEMBL30557228 | 0.66 | CYP19A1 (0.58) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235809-A1 | CGAS INHIBITORS | ELI LILLY AND COMPANY (US) | 2023-12-07 | — | — | WO | disclosed |