SCHEMBL30685007

SCHEMBL30685007

N#Cc1ccc(CCC(=O)NC23CC4CC(CC(N)(C4)C2)C3)cc1

nearest known ligand 0.63

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ DPP8 Q6V1X1 5/20 0.63
▸ DPP9 Q86TI2 5/20 0.63
▸ NPC1 O15118 1/20 0.46
▸ RAB9A P51151 1/20 0.46
▸ MEN1 O00255 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ PGR P06401 4/20 0.41
▸ EPHX2 P34913 3/20 0.41
▸ PBK Q96KB5 2/20 0.39
▸ GAA P10253 2/20 0.39
▸ ALDH1A1 P00352 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ FNTA P49354 1/20 0.38
▸ FNTB P49356 1/20 0.38
▸ PGGT1B P53609 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30685095 0.78 DPP9 (1.00) DPP8DPP9
SCHEMBL27356247 0.78 DPP9 (1.00) DPP8DPP9
SCHEMBL2637894 0.72 FAAH (0.51) DPP8DPP9MEN1KMT2APGR
SCHEMBL27356238 0.71 DPP9 (0.77) DPP8DPP9
SCHEMBL1937671 0.70 NPC1 (0.84) NPC1RAB9AMEN1KMT2AEPHX2
SCHEMBL27357819 0.70 DPP9 (0.81) DPP8DPP9
SCHEMBL3374604 0.70 JAK2 (0.51) DPP8DPP9RAB9AEPHX2PBK
SCHEMBL31284345 0.68 CTSB (0.58) DPP8DPP9MEN1KMT2AGAA
SCHEMBL8785064 0.68 NPC1 (0.55) NPC1RAB9AMEN1KMT2AEPHX2
SCHEMBL26240809 0.68 DPP8 (0.50) DPP8DPP9PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250353833-A1 DPP9 BINDING COMPOUNDS UNIV ANTWERPEN (BE) 2025-11-20 — — US disclosed
WO-2023233024-A1 DPP9 BINDING COMPOUNDS UNIVERSITEIT ANTWERPEN (BE) 2023-12-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250353833-A1 DPP9 BINDING COMPOUNDS DPP9, DPP7, DPP3 DPP8 5/4885DPP9 1/4885NPC1 1617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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