Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 2/20 | 0.49 |
| ▸ | IL23R | Q5VWK5 | 6/20 | 0.49 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | CCKAR | P32238 | 1/20 | 0.47 |
| ▸ | CCKBR | P32239 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30444033 | 0.91 | ACE (0.54) | MC4RKISS1RACE | |
| SCHEMBL30645551 | 0.88 | PRMT1 (0.57) | PRMT1IL23RKISS1RCCKARCCKBR | |
| SCHEMBL29772708 | 0.88 | PRMT1 (0.54) | PRMT1OPRD1OPRM1NPBWR1ACE | |
| SCHEMBL31659444 | 0.88 | CCKAR (0.54) | PRMT1OPRD1OPRM1NPBWR1MC4R | |
| SCHEMBL30725660 | 0.86 | IL23R (0.51) | PRMT1NPBWR1IL23RACE | |
| SCHEMBL30866237 | 0.86 | NPBWR1 (0.55) | PRMT1OPRD1OPRM1NPBWR1IL23R | |
| SCHEMBL30645560 | 0.86 | PRMT1 (0.60) | PRMT1OPRD1IL23RKISS1RCCKAR | |
| SCHEMBL26421593 | 0.86 | PRMT1 (0.55) | PRMT1OPRD1NPBWR1MC4RIL23R | |
| SCHEMBL20694561 | 0.86 | PRMT1 (0.54) | PRMT1OPRD1NPBWR1MC4RKISS1R | |
| SCHEMBL31593302 | 0.85 | NPBWR1 (0.54) | PRMT1OPRD1NPBWR1MC4RIL23R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117089572-A | Low off-target base editor and construction thereof | 中国科学院天津工业生物技术研究所 | 2023-11-21 | — | — | CN | disclosed |