SCHEMBL29772708

SCHEMBL29772708

N=C(N)NCCC[C@H](NC(=O)CNC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ PRMT1 Q99873 1/20 0.54
▸ OPRM1 P35372 2/20 0.53
▸ OPRD1 P41143 2/20 0.53
▸ KDM4E B2RXH2 1/20 0.51
▸ MEN1 O00255 1/20 0.51
▸ LMNA P02545 1/20 0.51
▸ MPO P05164 1/20 0.51
▸ MAPT P10636 1/20 0.51
▸ TSHR P16473 1/20 0.51
▸ BLM P54132 1/20 0.51
▸ PMP22 Q01453 1/20 0.51
▸ KMT2A Q03164 1/20 0.51
▸ HIF1A Q16665 1/20 0.51
▸ NPBWR1 P48145 3/20 0.48
▸ HDAC8 Q9BY41 1/20 0.47
▸ ACHE P22303 4/20 0.46
▸ BCHE P06276 3/20 0.46
▸ ACE P12821 1/20 0.46
▸ ERAP2 Q6P179 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31190178 0.92 PRMT1 (0.54) PRMT1OPRM1OPRD1NPBWR1
SCHEMBL29480592 0.92 OPRD1 (0.57) PRMT1OPRM1OPRD1NPBWR1
SCHEMBL4947728 0.92 KDM4E (0.56) KDM4EMEN1LMNAMPOMAPT
SCHEMBL4947716 0.92 KDM4E (0.56) KDM4EMEN1LMNAMPOMAPT
SCHEMBL13605071 0.92 KDM4E (0.56) KDM4EMEN1LMNAMPOMAPT
SCHEMBL29799941 0.90 KDM4E (0.54) PRMT1KDM4EMEN1LMNAMPO
SCHEMBL29791696 0.90 CCKBR (0.53) PRMT1OPRM1OPRD1NPBWR1
SCHEMBL31659444 0.89 CCKAR (0.54) PRMT1OPRM1OPRD1NPBWR1
SCHEMBL30839329 0.89 KDM4E (0.53) KDM4EMEN1LMNAMPOMAPT
SCHEMBL31280438 0.89 PRMT1 (0.45) PRMT1OPRM1OPRD1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240294632-A1 ANTIBODIES SPECIFIC FOR STRUCTURALLY DISORDERED SEQUENCES XL-PROTEIN GMBH (DE) 2024-09-05 — — US claimed
CN-117120476-A Antibodies specific for structurally disordered sequences XL-普洛坦公司 2023-11-24 — — CN claimed
EP-4267628-A1 ANTIBODIES SPECIFIC FOR STRUCTURALLY DISORDERED SEQUENCES XL-protein GmbH (DE) 2023-11-01 — — EP claimed
WO-2022136582-A1 ANTIBODIES SPECIFIC FOR STRUCTURALLY DISORDERED SEQUENCES XL-PROTEIN GMBH (DE) 2022-06-30 — — WO claimed
US-20240294632-A1 ANTIBODIES SPECIFIC FOR STRUCTURALLY DISORDERED SEQUENCES XL-PROTEIN GMBH (DE) 2024-09-05 — — US disclosed
CN-117120476-A Antibodies specific for structurally disordered sequences XL-普洛坦公司 2023-11-24 — — CN disclosed
EP-4267628-A1 ANTIBODIES SPECIFIC FOR STRUCTURALLY DISORDERED SEQUENCES XL-protein GmbH (DE) 2023-11-01 — — EP disclosed
WO-2022136582-A1 ANTIBODIES SPECIFIC FOR STRUCTURALLY DISORDERED SEQUENCES XL-PROTEIN GMBH (DE) 2022-06-30 — — WO disclosed
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